DHEA (
dehydroepiandrosterone) is a hormone produced by both men and women. It often declines with age. Currently, it is classified as a
dietary supplement and is, therefore, available without a prescription. Because it is a supplement, there is very little regulation of the manufacturing and sale of this product.
DHEA is often claimed to be a wonder drug or a "fountain of youth." It is used for many different age-related conditions and is popular as a supplement to increase sexual desire or performance.
(Click DHEA Benefits for more information on what the supplement is used for.)
DHEA is a hormone. In the human body, it is mostly produced by the adrenal glands (small glands that sit above the kidneys). Researchers are not exactly sure what DHEA itself does, although it is known that the body transforms DHEA into other steroid hormones, such as testosterone and estrogen. It is difficult to predict to what extent the body will convert DHEA into testosterone or estrogen in any particular individual. Some people will convert DHEA mostly into testosterone, while others will mostly convert it into estrogen.
DHEA appears to work for several different uses. However, there are many claims that are completely unsubstantiated or greatly exaggerated
(see Does DHEA Work? for more information).
The best doses for this supplement have not been established. Studies have used varying doses, depending on several factors (including the condition being treated).
While low doses of DHEA are often well tolerated, high doses can cause significant side effects, including (but not limited to):
(Click DHEA Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
Many people may be able to take low doses of DHEA safely for short periods of time. However, long-term, high-dose use is probably not safe. Some people may be more likely to experience problems due to the supplement. Therefore, you should talk with your healthcare provider prior to taking it if you have:
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Is DHEA Safe? for more information, including any available warnings and precautions.)
What If I Take a DHEA Overdose?
It is not known exactly what to expect from an overdose of this substance. It is reasonable to expect that taking too much DHEA might cause hormone imbalances, especially with long-term use.
Refer to the label of your individual DHEA product for information on how to best store it. Keep this and other medications or supplements out of the reach of children.
