L-Arginine Drug Interactions

Blood pressure medications, certain erectile dysfunction medicines, and nitrates can interact negatively with L-arginine. Drug interactions with L-arginine may result in dangerously low blood pressure, which could cause dizziness, lightheadedness, or other problems. To avoid these complications, you should not combine L-arginine with any of these medications without your healthcare provider's approval and supervision.

 

An Introduction to L-Arginine Drug Interactions

Even though it is a dietary supplement (not a "drug"), L-arginine can potentially interact with a few medicines. Some of the medicines that may lead to L-arginine drug interactions include:
 

 

 

  • Nitrates, such as:

 

    • Isosorbide dinitrate (Dilatrate® SR, Isochron™, Isordil®)
    • Isosorbide mononitrate (Imdur®, Ismo®, Monoket®)
    • Nitroglycerin tablets or capsules (Nitroquick®, Nitrostat®, Nitro-Time®)
    • Nitroglycerin ointment (Nitro-Bid®)
    • Nitroglycerin patches (Minitran®, Nitrodisc®, Nitro-Dur®, Transderm-Nitro®, Transderm-NTG®)
    • Nitroglycerin spray (Nitrolingual®).

 

(L-Arginine Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;