L-arginine is a semi-essential amino acid. This means that a dietary intake of L-arginine is not typically necessary, as the body can usually make the amino acid on its own. However, levels can be low in people who have certain medical conditions, and supplementation with L-arginine may be beneficial in some situations.
L-arginine has several different functions within the cells of the human body, many of which are related to nitric oxide production. It is used in the body to make nitric oxide, an important substance that causes the blood vessels to relax. It may also have antioxidant properties. There is some research that suggests that it may inhibit angiotensin-converting enzymes (ACE), much like ACE inhibitor
blood pressure medications. L-arginine may also stimulate the production of certain hormones, such as growth hormones, prolactin, and insulin.
These are just a few of the ways that researchers think it may work for a variety of conditions. As more studies are done, more information will become available about how it works.
Early research suggests that it may be effective for several uses. However, some uses are more valid than others
(see Does L-Arginine Work? for more information).
The best doses of L-arginine have not yet been established. Studies have used varying doses, depending on the condition being treated.
Even though it is an amino acid, it can sometimes cause side effects, such as:
(Click L-Arginine Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
Drug Interactions With L-Arginine
Reasonable doses of L-arginine are probably safe for most people, especially if high-quality supplements are used (because they are less likely to be contaminated or have other problems). Some people are more likely than others to experience problems. Therefore, you should talk with your healthcare provider prior to taking L-arginine if you have:
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Is L-Arginine Safe? for more information, including any available warnings and precautions.)
What If I Take an Overdose?
It is not known what exactly to expect from an overdose, but it is reasonable to assume that taking too much of it may cause the usual side effects of L-arginine, but perhaps more severely.
Storage Methods for L-Arginine
Refer to the label of your individual product for information on how best to store it. Keep L-arginine out of the reach of children.
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