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Stendra Drug Interactions

Stendra Drug Interactions Explained

The following sections explain in detail the potentially negative reactions that can occur when Stendra is combined with any of the drugs listed above.
 
Alcohol
You should not consume more than three alcoholic drinks while taking Stendra, such as three glasses of wine or beer, or three shots of liquor. Doing so could cause problems, such as:
 
  • An increase in heart rate
  • A decrease in blood pressure (especially upon standing)
  • Dizziness
  • Lightheadedness
  • Headache.
 
Alpha Blockers
Combining Stendra with an alpha blocker can cause low blood pressure (hypotension). If your blood pressure gets too low, you might become dizzy, lightheaded, or faint. If you are taking an alpha blocker, you will be started on a lower Stendra dosage.
 
Blood Pressure Medications
If you take Stendra in combination with a blood pressure-lowering medicine, your blood pressure may become too low. If this happens, you might become dizzy, lightheaded, or faint. If you are taking blood pressure medicines, you may need a lower Stendra dosage.
 
CYP 3A4 Inducer Medications
The liver breaks down Stendra using enzymes known as CYP 3A4 enzymes. Certain medications known as CYP 3A4 inducers can increase the activity of these enzymes. Combining Stendra with one of these CYP 3A4 inducers may decrease the level of Stendra in your bloodstream, making it less effective. The manufacturer of Stendra recommends that this drug should not be taken with a CYP 3A4 inducer.
 
CYP 3A4 Inhibitor Medications
The liver breaks down Stendra using enzymes known as CYP 3A4 enzymes. Certain medications known as CYP 3A4 inhibitors can decrease the activity of these enzymes. Combining Stendra with one of these CYP 3A4 inhibitors may increase the level of Stendra in your bloodstream, increasing your risk for serious side effects.
 
The maximum recommended Stendra dose in people using moderate CYP 3A4 inhibitors is Stendra 50 mg, no more often than once a day. People taking strong CYP 3A4 inhibitors should not use Stendra. Your healthcare provider will know which CYP 3A4 inhibitors are strong inhibitors and which are moderate inhibitors.
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