Drug Interactions With Tribulus

Lithium products and diabetes medications may potentially cause drug interactions with Tribulus. The dietary supplement could increase the risk of low blood sugar due to diabetes medicines and may increase the level of lithium in the blood, which can lead to lithium toxicity. In order to help prevent Tribulus interactions, it is important to tell your healthcare provider about all other drugs you are taking.

An Introduction to Interactions With Tribulus

Even though it is a natural herbal supplement, Tribulus can potentially interact with a few medicines. Some of the medicines that may lead to Tribulus drug interactions include:
 

Tribulus Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Tribulus is combined with any of the drugs listed above.
 
Diabetes Medications
Theoretically, Tribulus could increase the risk of low blood sugar (hypoglycemia) due to diabetes medications. If you have diabetes, check with your healthcare provider before taking this supplement. You may need to monitor your blood sugar more often.
 
Lithium
In theory, Tribulus may have a diuretic effect. Since diuretics can increase the level of lithium in the blood, it is possible that Tribulus could increase the risk of lithium toxicity. Check with your healthcare provider before taking lithium with this supplement.
 

Final Thoughts on Drug Interactions With Tribulus

It is possible that not every drug interaction with Tribulus was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the interactions that may apply to you.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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