It is possible for certain medications to negatively interact with yohimbe. Interactions may potentially occur that could increase your risk of developing dangerous (and even life-threatening) side effects. Some of the medications that could cause yohimbe drug interactions include blood pressure medications, MAOIs, and tricyclic antidepressants. To avoid any problems, make sure to tell your healthcare provider about any medications you are taking before starting yohimbe.
Even though yohimbe is a natural product, it can potentially interact with some medicines. Some of these medicines that may lead to yohimbe interactions include: