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Yohimbe Safety

Specific Yohimbe Warnings and Precautions

Some of the warnings and precautions to be aware of concerning the safety of yohimbe include the following:
  • Do not take yohimbe if you have heart disease or heart problems of any kind. Yohimbe can be especially dangerous for people with these types of problems.
  • Yohimbe can make anxiety disorders, bipolar disorder, or schizophrenia worse. If you have an anxiety disorder or schizophrenia, it is probably a good idea to avoid yohimbe supplements.
  • Theoretically, yohimbe could make the symptoms of an enlarged prostate worse. If you have an enlarged prostate, check with your healthcare provider before taking yohimbe.
  • If you have depression, do not take yohimbe (for any use) without your healthcare provider's approval. There is some concern that yohimbe could increase the risk of suicidal tendencies in some people with depression.
  • Yohimbe could cause low blood sugar (hypoglycemia) in people with diabetes. If you have diabetes, check with your healthcare provider before taking a yohimbe supplement.
  • Do not take yohimbe if you have high or low blood pressure. Low doses of yohimbe can cause high blood pressure, while high doses of yohimbe are likely to cause dangerously low blood pressure.
  • Do not take yohimbe if you have kidney disease, as yohimbe can cause water retention (which can be dangerous in people with kidney disease).
  • The liver helps to remove the active compounds in yohimbe from the body. If you have liver disease, your body may not handle yohimbe as well as normal.
  • Yohimbe may interact with some medications (see Yohimbe Drug Interactions).
  • Yohimbe is not considered safe for pregnant or breastfeeding women (see Yohimbe and Pregnancy and Yohimbe and Breastfeeding).
  • If you decide to use supplements (such as yohimbe), what you see on the label may not reflect what is in the bottle. For example, some herbal supplements have been found to be contaminated with heavy metals or prescription drugs, and some have been found to have much more or much less of the featured ingredient than their label states. 
Therefore, make sure the manufacturer of your yohimbe is a trusted and reputable manufacturer. It is a good sign if a manufacturer abides by the rules of Good Manufacturing Practices (GMP) for drugs. It is also a good sign if a product has the United States Pharmacopoeia (USP) seal, which means that the product has been independently tested and shown to contain the correct ingredients in the amounts listed on the label. Your pharmacist is a good resource for information about which manufacturers are the most reputable.
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